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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62048 Species: Rattus norvegicus RGD Object: Gene Symbol: Top2a Name: topoisomerase (DNA) II alpha

Acc ID: CHEBI:3537 Term: cefaloridine Definition: A cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side groups. CasRN: 50-59-9 Chemical ID: MESH:D002509

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Cephaloridine results in decreased expression of TOP2A mRNA	PMID:18500788