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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3046
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk3
Name: mitogen activated protein kinase 3
Acc ID: CHEBI:3537
Term: cefaloridine
Definition: A cephalosporin compound having pyridinium-1-ylmethyl and 2-thienylacetamido side-groups. A first-generation semisynthetic derivative of cephalosporin C.
Chemical ID: MESH:D002509
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk3increases activityEXP 6480464CTDCephaloridine results in increased activity of MAPK3 proteinPMID:16154539
Mapk3increases phosphorylationEXP 6480464CTDCephaloridine results in increased phosphorylation of MAPK3 proteinPMID:16272694
Mapk3multiple interactionsEXP 6480464CTDThymic Factor, Circulating inhibits the reaction [Cephaloridine results in increased phosphorylation of MAPK3 protein]PMID:16272694
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