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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2081 Species: Rattus norvegicus RGD Object: Gene Symbol: Akt1 Name: v-akt murine thymoma viral oncogene homolog 1

Acc ID: CHEBI:35170 Term: vanadium(0) Definition: An elemental vanadium that has formula V. CasRN: 7440-62-2 Chemical ID: MESH:D014639

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:735336	6480464	CTD	PRKCI protein mutant form inhibits the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein] PRKCA protein affects the reaction [Vanadium results in increased phosphorylation of and results in increased activity of AKT1 protein]	PMID:14971662