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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735797
Species: Mus musculus
RGD Object: Gene
Symbol: Trpv4
Name: transient receptor potential cation channel, subfamily V, member 4
Acc ID: CHEBI:34956
Term: ruthenium red
Definition: A ruthenium coordination entity that has formula H42N14O2Ru3.6Cl.
Chemical ID: MESH:D012430
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpv4decreases activityISOTrpv4 (Rattus norvegicus)6480464CTDRuthenium Red results in decreased activity of TRPV4 proteinPMID:20064552
Trpv4multiple interactionsISOTrpv4 (Rattus norvegicus)6480464CTD[Ruthenium Red results in decreased activity of TRPV4 protein] which results in decreased susceptibility to Buthionine SulfoximinePMID:20064552
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