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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620707 Species: Rattus norvegicus RGD Object: Gene Symbol: Tff1 Name: trefoil factor 1

Acc ID: CHEBI:34916 Term: phenothrin Definition: A cyclopropane that has formula C23H26O3. CasRN: 26002-80-2 Chemical ID: MESH:C006166

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	ISO	RGD:1344671	6480464	CTD	ICI 164384 inhibits the reaction [phenothrin results in increased expression of TFF1 mRNA]	PMID:10064545
increases expression	ISO	RGD:1344671	6480464	CTD	phenothrin results in increased expression of TFF1 mRNA	PMID:10064545 PMID:15118252
increases expression	ISO	RGD:1344671	6480464	CTD	phenothrin results in increased expression of TFF1 mRNA	PMID:15118252 PMID:10064545