Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708572
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Arl6ip5
Name: ADP-ribosylation factor like GTPase 6 interacting protein 5
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Arl6ip5affects response to substanceISOArl6ip5 (Mus musculus)6480464CTDARL6IP5 protein affects the susceptibility to ParaquatPMID:28428137
Arl6ip5increases expressionISOArl6ip5 (Mus musculus)6480464CTDParaquat results in increased expression of ARL6IP5PMID:28428137
Arl6ip5increases expressionISOARL6IP5 (Homo sapiens)6480464CTDParaquat results in increased expression of ARL6IP5 proteinPMID:28428137
Arl6ip5multiple interactionsISOArl6ip5 (Mus musculus)6480464CTDARL6IP5 protein affects the reaction [Paraquat affects the expression of NFE2L2 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the expression of TH protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK3 protein]PMID:28428137
Arl6ip5multiple interactionsISOARL6IP5 (Homo sapiens)6480464CTDARL6IP5 protein affects the reaction [Paraquat affects the expression of NFE2L2 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK3 protein]PMID:28428137
Go Back to source page   Continue to Ontology report