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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628847
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk9
Name: mitogen-activated protein kinase 9
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk9increases expressionEXP 6480464CTDParaquat results in increased expression of MAPK9 mRNAPMID:18198484
Mapk9increases phosphorylationEXP 6480464CTDParaquat results in increased phosphorylation of MAPK9 proteinPMID:16687388 PMID:28474156
Mapk9multiple interactionsEXP 6480464CTDpyrazolanthrone inhibits the reaction [Paraquat results in increased phosphorylation of MAPK9 protein]PMID:16687388 PMID:28474156
Mapk9increases phosphorylationISOMAPK9 (Homo sapiens)6480464CTDParaquat results in increased phosphorylation of MAPK9 proteinPMID:28474156
Mapk9increases phosphorylationISOMapk9 (Mus musculus)6480464CTDParaquat results in increased phosphorylation of MAPK9 proteinPMID:28215578
Mapk9multiple interactionsISOMAPK9 (Homo sapiens)6480464CTDMFN2 inhibits the reaction [Paraquat results in increased phosphorylation of MAPK9 protein]; Paraquat results in increased phosphorylation of and results in increased activity of MAPK9 protein; pyrazolanthrone inhibits the reaction [Paraquat results in increased phosphorylation of MAPK9 protein]PMID:17018646 PMID:28215578 PMID:28474156
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