• View As List
• View As Table

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62178 Species: Mus musculus RGD Object: Gene Symbol: Timp2 Name: tissue inhibitor of metalloproteinase 2

Acc ID: CHEBI:34905 Term: paraquat Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions. CasRN: 4685-14-7 Chemical ID: MESH:D010269

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	Paraquat results in decreased expression of TIMP2 mRNA	PMID:17215068
affects expression	ISO	RGD:61312	6480464	CTD	Paraquat affects the expression of TIMP2 mRNA	PMID:16854511
multiple interactions	ISO	RGD:61312	6480464	CTD	Ambroxol affects the reaction [Paraquat results in increased expression of TIMP2 mRNA]	PMID:21921364