GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Abcb1a | affects expression | EXP | | 6480464 | CTD | Paraquat affects the expression of ABCB1A mRNA | PMID:16854511 | Abcb1a | multiple interactions | ISO | Abcb1a (Mus musculus) | 6480464 | CTD | [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of LCN2 mRNA; [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of NQO1 mRNA; ABCB1A protein results in increased export of and results in decreased susceptibility to Paraquat | PMID:25015657 | Abcb1a | multiple interactions | ISO | ABCB1 (Homo sapiens) | 6480464 | CTD | [Doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paraquat; ABCB1 protein affects the reaction [Doxorubicin results in decreased susceptibility to Paraquat]; ABCB1 protein results in increased export of and results in decreased susceptibility to Paraquat; valspodar inhibits the reaction [ABCB1 protein results in increased export of Paraquat] | PMID:23220037 PMID:25015657 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |