An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID:
MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Paraquat results in increased expression of HMOX1; Paraquat results in increased expression of HMOX1 mRNA; Paraquat results in increased expression of HMOX1 protein
[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with ginkgolide C] results in increased expression of HMOX1 protein; [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of HMOX1 mRNA; alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Curcumin inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Estradiol affects the reaction [Paraquat affects the expression of HMOX1 protein]; ginkgolide C promotes the reaction [Paraquat results in increased expression of HMOX1 protein]; Hemin promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; MIR136 promotes the reaction [Paraquat results in decreased expression of HMOX1 protein]; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA]; Quercetin inhibits the reaction [Paraquat results in increased expression of HMOX1]; Resveratrol inhibits the reaction [MIR136 promotes the reaction [Paraquat results in decreased expression of HMOX1 protein]]; Resveratrol inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]; SB 203580 promotes the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of HMOX1 mRNA]
2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of HMOX1 protein]; [SIRT6 protein mutant form results in decreased activity of SIRT6 protein] inhibits the reaction [Paraquat promotes the reaction [SMARCA4 protein binds to HMOX1 enhancer]]; [SIRT6 protein mutant form results in decreased activity of SIRT6 protein] inhibits the reaction [Paraquat results in increased expression of HMOX1 mRNA]; naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Paraquat results in increased expression of HMOX1 protein]; Paraquat affects the reaction [APOD protein affects the expression of HMOX1 protein]; Paraquat promotes the reaction [POLR2A protein modified form binds to HMOX1 gene]; Paraquat promotes the reaction [SIRT6 protein binds to HMOX1 gene]; Paraquat promotes the reaction [SMARCA4 protein binds to HMOX1 enhancer]; Paraquat promotes the reaction [SMARCC2 protein binds to HMOX1 enhancer]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]; resolvin D1 analog inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; resolvin D1 inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; Resveratrol promotes the reaction [Paraquat results in increased activity of HMOX1 protein]; rhyncophylline inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; SIRT1 protein affects the reaction [Paraquat affects the activity of HMOX1 protein]; SIRT6 promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; SIRT6 protein promotes the reaction [Paraquat promotes the reaction [POLR2A protein modified form binds to HMOX1 gene]]; SIRT6 protein promotes the reaction [Paraquat promotes the reaction [SMARCA4 protein binds to HMOX1 enhancer]]; SIRT6 protein promotes the reaction [Paraquat promotes the reaction [SMARCC2 protein binds to HMOX1 enhancer]]; SMARCC2 protein mutant form inhibits the reaction [Paraquat results in increased expression of HMOX1 mRNA]; SMARCC2 protein promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]
[Paraquat co-treated with Antigens, Dermatophagoides] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein; [Paraquat co-treated with naringenin] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Quercetin] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of HMOX1 protein; [Quercetin co-treated with Paraquat] results in increased expression of HMOX1 protein; [SIRT6 protein results in decreased susceptibility to Paraquat] inhibits the reaction [NFE2L2 protein binds to HMOX1 enhancer]; [SNCA protein co-treated with Paraquat co-treated with Dopamine] results in increased expression of HMOX1 protein; NFE2L2 mRNA promotes the reaction [Paraquat promotes the reaction [SIRT6 protein binds to HMOX1 gene]]; Paraquat promotes the reaction [SIRT6 protein binds to HMOX1 gene]; Resveratrol promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of HMOX1 protein]