Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708351
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kdm3a
Name: lysine demethylase 3A
Acc ID: CHEBI:34887
Term: nickel dichloride
Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2.
Chemical ID: MESH:C022838
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kdm3aaffects expressionEXP 6480464CTDnickel chloride affects the expression of KDM3A mRNAPMID:22110744
Kdm3aincreases expressionISOKDM3A (Homo sapiens)6480464CTDnickel chloride results in increased expression of KDM3A mRNA; nickel chloride results in increased expression of KDM3A proteinPMID:17312168 PMID:21455298 PMID:22318714
Kdm3amultiple interactionsISOKDM3A (Homo sapiens)6480464CTDAscorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A mRNA]; Ascorbic Acid inhibits the reaction [nickel chloride results in increased expression of KDM3A protein]PMID:22318714
Go Back to source page   Continue to Ontology report