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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1318374 Species: Homo sapiens RGD Object: Gene Symbol: SIRT1 Name: sirtuin 1

Acc ID: CHEBI:34887 Term: nickel dichloride Definition: A compound of nickel and chloride in which the ratio of nickel (in the +2 oxidation state) to chloride is 1:2. CasRN: 7718-54-9 Chemical ID: MESH:C022838

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases expression	EXP		6480464	CTD	nickel chloride results in increased expression of SIRT1 mRNA	PMID:17547211