GENE - CHEMICAL INTERACTIONS REPORT
RGD ID:
735711
Species:
Homo sapiens
RGD Object:
Gene
Symbol:
CYP1A2
Name:
cytochrome P450, family 1, subfamily A, polypeptide 2
Acc ID:
CHEBI:34873
Term:
N-nitrosodiethylamine
Definition:
A nitrosamine that has formula C4H10N2O.
CasRN:
55-18-5
Chemical ID:
MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
multiple interactions ISO RGD:10438 6480464 CTD [dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA PMID:20118626 multiple interactions ISO RGD:2459 6480464 CTD [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA PMID:18164116 PMID:20045035 multiple interactions ISO RGD:2459 6480464 CTD [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of CYP1A2 mRNA PMID:20360939 multiple interactions ISO RGD:2459 6480464 CTD [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A2 mRNA PMID:20033131 decreases expression ISO RGD:2459 6480464 CTD Diethylnitrosamine results in decreased expression of CYP1A2 mRNA PMID:20360939 PMID:19638242 multiple interactions ISO RGD:2459 6480464 CTD [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP1A2 mRNA PMID:18253720 multiple interactions ISO RGD:2459 6480464 CTD [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA PMID:18754104 multiple interactions ISO RGD:2459 6480464 CTD [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A2 mRNA PMID:20045035 PMID:18164116 decreases expression ISO RGD:2459 6480464 CTD Diethylnitrosamine results in decreased expression of CYP1A2 mRNA PMID:19638242 PMID:20360939 multiple interactions ISO RGD:2459 6480464 CTD [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA PMID:22687989 multiple interactions ISO RGD:2459 6480464 CTD Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA] PMID:22129741 
