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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631409
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hsp90aa1
Name: heat shock protein 90 alpha family class A member 1
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hsp90aa1increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of HSP90AA1 mRNAPMID:19638242
Hsp90aa1multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSP90AA1 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of HSP90AA1 mRNAPMID:18544905 PMID:28943392
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