GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620381
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gstm3
Name: glutathione S-transferase mu 3
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that has formula C4H10N2O.
CasRN: 55-18-5
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDDiethylnitrosamine results in increased expression of GSTM3 mRNA

PMID:14965361
decreases expressionEXP 6480464CTDDiethylnitrosamine results in decreased expression of GSTM3 mRNA

PMID:19638242
multiple interactionsEXP 6480464CTD[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA

PMID:18253720
PMID:18775883
multiple interactionsISORGD:16201176480464CTD[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA

PMID:17917374
multiple interactionsEXP 6480464CTD[Copper co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA

[Copper co-treated with Diethylnitrosamine co-treated with Iron] results in increased expression of GSTM3 mRNA

PMID:20302851
multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA

PMID:18544905
multiple interactionsEXP 6480464CTD[Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA

PMID:18775883
PMID:18253720
multiple interactionsEXP 6480464CTD[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTM3 mRNA

PMID:22129741
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