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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620268
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abcc6
Name: ATP binding cassette subfamily C member 6
Acc ID: CHEBI:34873
Term: N-nitrosodiethylamine
Definition: A nitrosamine that is N-ethylethanamine substituted by a nitroso group at the N-atom.
Chemical ID: MESH:D004052
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abcc6decreases expressionEXP 6480464CTDDiethylnitrosamine results in decreased expression of ABCC6 mRNAPMID:19638242
Abcc6multiple interactionsEXP 6480464CTD[Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ABCC6 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC6 mRNA; [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of ABCC6 mRNAPMID:17602206 PMID:18544905 PMID:28943392
Abcc6multiple interactionsISOAbcc6 (Mus musculus)6480464CTD[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC6 mRNAPMID:17917374
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