GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | decreases expression | EXP | | 6480464 | CTD | Diethylnitrosamine results in decreased expression of PPARG mRNA; Diethylnitrosamine results in decreased expression of PPARG protein | PMID:24954034 | Pparg | multiple interactions | EXP | | 6480464 | CTD | [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of PPARG mRNA; [Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of PPARG protein; [Diethylnitrosamine co-treated with Dietary Fats] results in increased expression of PPARG mRNA; Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of PPARG mRNA]; Hesperidin inhibits the reaction [[Carbon Tetrachloride co-treated with Diethylnitrosamine] results in decreased expression of PPARG protein] | PMID:28935427 PMID:30298849 | Pparg | decreases response to substance | ISO | Pparg (Mus musculus) | 6480464 | CTD | PPARG protein results in decreased susceptibility to Diethylnitrosamine | PMID:20512989 | |
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