GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Met | affects response to substance | EXP | | 6480464 | CTD | MET affects the susceptibility to Diethylnitrosamine | PMID:19123478 | Met | decreases expression | ISO | Met (Mus musculus) | 6480464 | CTD | Diethylnitrosamine results in decreased expression of MET protein | PMID:20583210 | Met | increases response to substance | ISO | Met (Mus musculus) | 6480464 | CTD | MET protein results in increased susceptibility to Diethylnitrosamine | PMID:17942915 | Met | multiple interactions | ISO | Met (Mus musculus) | 6480464 | CTD | CTNNB1 protein promotes the reaction [Diethylnitrosamine results in decreased expression of MET protein]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ATP13A4 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ATP2A1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of CTSC mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of DBP mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of GADD45B mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of GKN3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of H2-D1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of IFITM5 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ITPKB mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of KRT13 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of LANCL1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of MS4A1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of OR6C202 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of PLA2G2C mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of SLC22A4 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of TSGA10 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of ZFP3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABCA3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ABTB2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ACO2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AFM mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGXT mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AHSA1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of AP2B1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARG1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGAP19 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGAP5 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARHGEF19 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARL5A mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ARRB1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASB14 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ASNS mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATP11C mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ATP8B4 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of B2M mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of B3GAT1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of BCKDHB mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of BST2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of C1QC mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CAPZA2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CDK2AP2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CIB3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CLOCK mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of COL6A1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CPEB2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CTSS mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYB5A mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2D13 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP2D22 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP3A13 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP3A44 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of CYP4F16 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DCT mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DGUOK mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DUSP1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of DYNLT1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ELOB mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPOR mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EVI2B mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of EXOC8 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of FAM20B mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of G6PC1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GADD45G mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GBP9 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GFER mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GIMAP7 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GLO1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of GSTM2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of H19 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of H2-BL mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HIRA mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HNRNPC mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HSD17B11 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HSPA1B mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HSPD1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of HTR2A mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ID3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of IGF1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of IGFBP1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KCNAB1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KCNJ14 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KLF10 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of KLF12 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of LRP1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MALAT1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MEGF9 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MKI67 protein]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MUG1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of MUG2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NAT8 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NAT8F5 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NDRG1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NDUFA12 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NDUFA7 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NKX6-2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NLRP3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NPR2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of NRN1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OAT mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OLFM1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OR52E4 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of OR5AC21 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of P2RX4 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of P2RX7 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PALMD mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PARD6A mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PEBP1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PIGR mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLA1A mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLA2G2C mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PLAAT3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PNRC1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PPM1K mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of PPP1R37 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RAB6B mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RABGAP1L mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBBP4 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RBP1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RHOH mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL17 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL27A mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL32 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL35 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL41 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of RPL9 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SBP mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCD2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCGB1C1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCN8A mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SCTR mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SERF2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SH2D6 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC16A10 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC19A2 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC25A48 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SLC47A1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SMOX mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SOD1 protein]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ST7 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of SYT5 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TLN1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMEM98 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMPRSS3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TMSB4X mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TRAPPC5 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of TRPM1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of UBC mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of UGT2B1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of UTRN mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VEPH1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VIM mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VSIG10 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of VSIG4 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of WWOX mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZCCHC18 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZFP300 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZFP36L1 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased expression of ZZZ3 mRNA]; MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein]; MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCA protein]; MET protein inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of PRKCB protein] | PMID:17942915 PMID:20583210 | | ||||||||||||||||||||||
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