GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Cyp1a1 | increases expression | EXP | | 6480464 | CTD | Diethylnitrosamine results in increased expression of CYP1A1 mRNA; Diethylnitrosamine results in increased expression of CYP1A1 protein | PMID:21295105 PMID:23494807 PMID:27565560 | Cyp1a1 | multiple interactions | EXP | | 6480464 | CTD | [Diethylnitrosamine co-treated with alpha-hexachlorocyclohexane] results in increased expression of CYP1A1 protein; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CYP1A1 protein; [Diethylnitrosamine co-treated with oxfendazole co-treated with isoquercitrin] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of CYP1A1 mRNA; [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Mastic Resin co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Omeprazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Orphenadrine co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [oxfendazole co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 protein; allyl sulfide inhibits the reaction [Diethylnitrosamine results in increased expression of CYP1A1 mRNA]; beta-Naphthoflavone promotes the reaction [Diethylnitrosamine results in increased expression of CYP1A1 mRNA]; Diethylnitrosamine results in increased expression of and results in increased activity of CYP1A1 protein; Melatonin inhibits the reaction [[Diethylnitrosamine co-treated with oxfendazole] results in increased expression of CYP1A1 mRNA] | PMID:11165752 PMID:18164116 PMID:18648771 PMID:18754104 PMID:18977376 PMID:20033131 PMID:20045035 PMID:21295105 PMID:22129741 PMID:22687989 PMID:23494807 PMID:23665939 | Cyp1a1 | multiple interactions | ISO | Cyp1a1 (Mus musculus) | 6480464 | CTD | 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [[3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA]; [3,4,5,3',4'-pentachlorobiphenyl co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA] which results in increased abundance of Reactive Oxygen Species; [dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA; [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in increased expression of CYP1A1 mRNA; Diethylnitrosamine promotes the reaction [AHR protein binds to CYP1A1 promoter]; Plant Extracts inhibits the reaction [[[dicyclanil co-treated with Diethylnitrosamine] results in increased expression of CYP1A1 mRNA] which results in increased abundance of Reactive Oxygen Species]; Plant Extracts inhibits the reaction [[Diethylnitrosamine co-treated with dicyclanil] results in increased expression of CYP1A1 mRNA] | PMID:15535986 PMID:17162532 PMID:19182440 PMID:19690152 PMID:20101389 PMID:20118626 PMID:23457121 | |
Go Back to source page | Continue to Ontology report |