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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70500
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mapk1
Name: mitogen activated protein kinase 1
Acc ID: CHEBI:34860
Term: N,N'-diphenyl-1,4-phenylenediamine
Definition: An N-substituted diamine that is 1,4-phenylenediamine in which one hydrogen from each amino group is replaced by a phenyl group.
Chemical ID: MESH:C004845
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mapk1multiple interactionsEXP 6480464CTDN,N'-diphenyl-4-phenylenediamine inhibits the reaction [zinc chloride results in increased phosphorylation of MAPK1 protein]; N,N'-diphenyl-4-phenylenediamine inhibits the reaction [Zinc results in increased phosphorylation of MAPK1 protein]PMID:16960431
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