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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 631344
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Abca1
Name: ATP binding cassette subfamily A member 1
Acc ID: CHEBI:34779
Term: glyoxal
Definition: The dialdehyde that is the smallest possible and which consists of ethane having oxo groups on both carbons.
Chemical ID: MESH:D006037
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Abca1increases degradationISOAbca1 (Mus musculus)6480464CTDGlyoxal results in increased degradation of ABCA1 proteinPMID:15983222
Abca1multiple interactionsISOAbca1 (Mus musculus)6480464CTDGlyoxal inhibits the reaction [ABCA1 protein binds to APOA1 protein]PMID:15983222
Abca1multiple interactionsISOABCA1 (Homo sapiens)6480464CTDGlyoxal inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]PMID:15983222
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