Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	2869
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Igf1r
Name:	insulin-like growth factor 1 receptor

Acc ID:	CHEBI:34741
Term:	equol
Definition:	A hydroxyisoflavan that has formula C15H14O3.
Chemical ID:	MESH:D060754

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Igf1r	decreases expression	ISO	IGF1R (Homo sapiens)	6480464	CTD	Equol results in decreased expression of IGF1R mRNA	PMID:16865672

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.