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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621812
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cxcl3
Name: C-X-C motif chemokine ligand 3
Acc ID: CHEBI:34718
Term: 1-chloro-2,4-dinitrobenzene
Definition: A C-nitro compound that is chlorobenzene carrying a nitro substituent at each of the 2- and 4-positions.
Chemical ID: MESH:D004137
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl3increases expressionISOCXCL1 (Homo sapiens)6480464CTDDinitrochlorobenzene results in increased expression of CXCL1 mRNAPMID:20146380 PMID:20713136
Cxcl3increases expressionISOCxcl3 (Mus musculus)6480464CTDDinitrochlorobenzene results in increased expression of CXCL1 mRNAPMID:19647056 PMID:21404309 PMID:28219650 PMID:28826779
Cxcl3multiple interactionsISOCxcl3 (Mus musculus)6480464CTDNFE2L2 protein inhibits the reaction [Dinitrochlorobenzene results in increased expression of CXCL1 mRNA]PMID:28219650
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