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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 71019
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Egln3
Name: egl-9 family hypoxia-inducible factor 3
Acc ID: CHEBI:34682
Term: diazinon
Definition: A member of the class of pyrimidines that is pyrimidine carrying an isopropyl group at position 2, a methyl group at position 6 and a (diethoxyphosphorothioyl)oxy group at position 4.
Chemical ID: MESH:D003976
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egln3affects expressionEXP 6480464CTDDiazinon affects the expression of EGLN3 mRNAPMID:22546817
Egln3increases methylationISOEGLN3 (Homo sapiens)6480464CTDDiazinon results in increased methylation of EGLN3 genePMID:22964155
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