GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esr1 | affects binding | ISO | ESR1 (Homo sapiens) | 6480464 | CTD | di-n-octyl phthalate analog binds to ESR1 protein | PMID:15464722 | Esr1 | multiple interactions | ISO | Esr1 (Mus musculus) | 6480464 | CTD | [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diethyl phthalate co-treated with di-n-octyl phthalate co-treated with diisodecyl phthalate co-treated with diisononyl phthalate] results in increased expression of ESR1 protein; [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with diethyl phthalate co-treated with diisononyl phthalate co-treated with di-n-octyl phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with diisodecyl phthalate] results in increased expression of ESR1 protein | PMID:35739755 PMID:37364641 | Esr1 | multiple interactions | ISO | ESR1 (Homo sapiens) | 6480464 | CTD | di-n-octyl phthalate inhibits the reaction [Estradiol results in increased activity of ESR1 protein] | PMID:28571686 | |
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