GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Ccl2 | increases expression | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Dextran Sulfate results in increased expression of CCL2 mRNA | PMID:19645018 PMID:20079348 PMID:31807802 | Ccl2 | increases secretion | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | Dextran Sulfate results in increased secretion of CCL2 protein | PMID:21858153 | Ccl2 | multiple interactions | ISO | Ccl2 (Mus musculus) | 6480464 | CTD | [RASSF1 gene mutant form results in increased susceptibility to Dextran Sulfate] which results in increased secretion of CCL2 protein; [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of CCL2 mRNA; Tetrachlorodibenzodioxin inhibits the reaction [Dextran Sulfate results in increased secretion of CCL2 protein] | PMID:21858153 PMID:24146755 PMID:29950665 | | ||||||||||||||||||||||
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