GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Pparg | increases expression | EXP | | 6480464 | CTD | Chlorpyrifos results in increased expression of PPARG mRNA | PMID:33994353 | Pparg | decreases expression | ISO | PPARG (Homo sapiens) | 6480464 | CTD | Chlorpyrifos results in decreased expression of PPARG mRNA; Chlorpyrifos results in decreased expression of PPARG protein | PMID:24793810 PMID:31509763 | Pparg | increases expression | ISO | Pparg (Mus musculus) | 6480464 | CTD | Chlorpyrifos results in increased expression of PPARG mRNA | PMID:37019170 | Pparg | multiple interactions | ISO | PPARG (Homo sapiens) | 6480464 | CTD | rosiglitazone inhibits the reaction [Chlorpyrifos results in decreased expression of PPARG protein] | PMID:24793810 | Pparg | multiple interactions | ISO | Pparg (Mus musculus) | 6480464 | CTD | [Chlorpyrifos co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG protein; Chlorpyrifos promotes the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of PPARG mRNA] | PMID:32017950 | |
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