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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619934
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2c6
Name: cytochrome P450, family 2, subfamily C, polypeptide 6
Acc ID: CHEBI:34575
Term: bisphenol F
Definition: A bisphenol that is methane in which two of the hydrogens have been replaced by 4-hydroxyphenyl groups.
Chemical ID: MESH:C008745
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c6increases glutathionylationISOCYP2C19 (Homo sapiens)6480464CTDCYP2C19 protein results in increased glutathionylation of 4,4'-bisphenol F; CYP2C19 protein results in increased glutathionylation of 4,4'-bisphenol F metabolitePMID:23470418
Cyp2c6increases hydroxylationISOCYP2C19 (Homo sapiens)6480464CTDCYP2C19 protein results in increased hydroxylation of 4,4'-bisphenol FPMID:23470418
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