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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69649
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Itpr2
Name: inositol 1,4,5-trisphosphate receptor, type 2
Acc ID: CHEBI:34524
Term: Adenophostin A
Definition: A disaccharide phosphate that has formula C16H26N5O18P3.
Chemical ID: MESH:C085029
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Itpr2increases activityISOItpr2 (Mus musculus)6480464CTDadenophostin A results in increased activity of ITPR2 proteinPMID:15201137
Itpr2multiple interactionsISOItpr2 (Mus musculus)6480464CTD2-aminoethoxydiphenyl borate inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]; [adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium; xestospongin C inhibits the reaction [[adenophostin A results in increased activity of ITPR2 protein] which results in increased transport of Calcium]PMID:15201137
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