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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:34440
Term: 4-nonylphenol
Definition: A member of the class of phenols that is phenol which is para-substituted with a nonyl group.
Chemical ID: MESH:C041594
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTD4-nonylphenol results in decreased expression of BCL2 mRNA; 4-nonylphenol results in decreased expression of BCL2 proteinPMID:26804764 PMID:27087316 PMID:27109770
Bcl2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with 4-nonylphenol] results in decreased expression of BCL2 mRNAPMID:30228064
Bcl2increases expressionISOBCL2 (Homo sapiens)6480464CTD4-nonylphenol results in increased expression of BCL2 mRNAPMID:15461258
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