GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Casp3 | multiple interactions | EXP | | 6480464 | CTD | [Carvedilol co-treated with aliskiren] inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Carvedilol inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; Carvedilol inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein]; Carvedilol inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Carvedilol inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein] | PMID:15380674 PMID:21044617 PMID:25245570 PMID:26036690 PMID:26982530 | Casp3 | multiple interactions | ISO | Casp3 (Mus musculus) | 6480464 | CTD | carvedilol inhibits the reaction [Cisplatin results in increased cleavage of and results in increased activity of CASP3 protein] | PMID:24012798 | Casp3 | multiple interactions | ISO | CASP3 (Homo sapiens) | 6480464 | CTD | carvedilol inhibits the reaction [Epinephrine results in increased activity of CASP3 protein] | PMID:10728402 | | ||||||||||||||||||||||
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