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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621400
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i3
Name: nuclear receptor subfamily 1, group I, member 3
Acc ID: CHEBI:34342
Term: 3-methylcholanthrene
Definition: A pentacyclic ortho- and peri-fused polycyclic arene consisting of a dihydrocyclopenta[ij]tetraphene ring system with a methyl substituent at the 3-position.
Chemical ID: MESH:D008748
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i3affects expressionEXP 6480464CTDMethylcholanthrene affects the expression of NR1I3 mRNAPMID:23273579
Nr1i3increases expressionISONR1I3 (Homo sapiens)6480464CTDMethylcholanthrene results in increased expression of NR1I3 mRNAPMID:19118567
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