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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3895
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Tph1
Name: tryptophan hydroxylase 1
Acc ID: CHEBI:34328
Term: 3-Amino-1-methyl-5H-pyrido[4,3-b]indole
Definition: A pyridoindole that has formula C12H11N3.
Chemical ID: MESH:C019133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tph1decreases activityISOTph1 (Mus musculus)6480464CTD3-amino-1-methyl-5H-pyrido(4,3-b)indole results in decreased activity of TPH1 proteinPMID:1989631
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