A pentachlorobiphenyl in which the chlorines are located at the 3, 4, 5, 3', and 4' positions.
Chemical ID:
MESH:C023035
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CCL2 protein]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; CAV1 affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; CAV1 gene mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 mRNA]; CAV1 gene mutant form promotes the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of NQO1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VCAM1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CAV1 mutant form inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased phosphorylation of and results in increased activity of MAPK3 protein]
3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of FYN protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased expression of KEAP1 protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in decreased phosphorylation of PRKCD protein]; 3,4,5,3',4'-pentachlorobiphenyl promotes the reaction [CAV1 mutant form results in increased phosphorylation of AKT1 protein]