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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70822 Species: Homo sapiens RGD Object: Gene Symbol: FGF2 Name: fibroblast growth factor 2 (basic)

Acc ID: CHEBI:34288 Term: 2-hydroxyethyl methacrylate Definition: An enoate ester that is the monomethacryloyl derivative of ethylene glycol. CasRN: 868-77-9 Chemical ID: MESH:C005044

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
multiple interactions	EXP		6480464	CTD	Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in increased secretion of FGF2 protein] anthra(1,9-cd)pyrazol-6(2H)-one inhibits the reaction [hydroxyethyl methacrylate results in increased secretion of FGF2 protein]	PMID:19176594
increases secretion	EXP		6480464	CTD	hydroxyethyl methacrylate results in increased secretion of FGF2 protein	PMID:19176594