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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61867
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Casp9
Name: caspase 9
Acc ID: CHEBI:34288
Term: 2-hydroxyethyl methacrylate
Definition: An enoate ester that is the monomethacryloyl derivative of ethylene glycol.
Chemical ID: MESH:C005044
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp9increases expressionISOCASP9 (Homo sapiens)6480464CTDhydroxyethyl methacrylate results in increased expression of CASP9 mRNAPMID:28184909
Casp9multiple interactionsISOCASP9 (Homo sapiens)6480464CTD3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [hydroxyethyl methacrylate results in increased expression of CASP9 mRNA]; 3-methyladenine inhibits the reaction [hydroxyethyl methacrylate results in increased expression of CASP9 mRNA]; Chloroquine inhibits the reaction [hydroxyethyl methacrylate results in increased expression of CASP9 mRNA]PMID:28184909
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