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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731580 Species: Mus musculus RGD Object: Gene Symbol: Hmgcr Name: 3-hydroxy-3-methylglutaryl-Coenzyme A reductase

Acc ID: CHEBI:34202 Term: 2,2',4,4',5,5'-hexachlorobiphenyl Definition: A hexachlorobiphenyl that has formula C12H4Cl6. CasRN: 35065-27-1 Chemical ID: MESH:C014024

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
decreases expression	EXP		6480464	CTD	2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of HMGCR mRNA	PMID:20005886