Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
NR1I2 gene mutant form inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP2B1 protein]; NR1I2 gene mutant form promotes the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of CYP2B1 mRNA]
2,4,5,2',4',5'-hexachlorobiphenyl binds to and results in increased activity of NR1I2 protein; 2,4,5,2',4',5'-hexachlorobiphenyl promotes the reaction [NR1I2 protein results in increased expression of CYP3A4]
2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of ALAS2 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of APEX2 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of APOL7C mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of ATP1B1 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of CAMP mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of CD200 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of CLPS mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of COMT mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of CYP4A12A mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of GAS2 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of GSS mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of GSTP3 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of IFT57 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of MARCO mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of MPO mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of OAS2 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of OPTN mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of PAPSS2 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of PCLAF mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of PDE4B mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of PIM1 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of PLA2G12A mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of PXK mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of RRM2 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of S100A9 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of SELENBP2 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of SERPINA3K mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of SIGLECH mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of SMARCA5 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of TGIF1 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of TOMM40L mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of UHRF1 mRNA]; 2,4,5,2',4',5'-hexachlorobiphenyl affects the reaction [NR1I2 protein affects the expression of WIPI1 mRNA]; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of BLVRB mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of EPB42 mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of FECH mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of KLF1 mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of MGST3 mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of PRDX2 mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of PRXL2A mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of SLCO1A1 mRNA; [NR1I2 protein affects the susceptibility to 2,4,5,2',4',5'-hexachlorobiphenyl] which affects the expression of SULT2A1 mRNA; REG1 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of NR1I2 mRNA]; TRY10 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of NR1I2 mRNA]; TYRP1 protein affects the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in decreased expression of NR1I2 mRNA]
