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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1303284
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Trpa1
Name: transient receptor potential cation channel, subfamily A, member 1
Acc ID: CHEBI:34055
Term: 1,2-naphthoquinone
Definition: The parent structure of the family of 1,2-naphthoquinones, in which the oxo groups of the quinone moiety are at positions 1 and 2 of the naphthalene ring. It is a metabolite of naphthalene and is found in diesel exhaust particles.
Chemical ID: MESH:C040756
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Trpa1increases activityISOTRPA1 (Homo sapiens)6480464CTD1,2-naphthoquinone results in increased activity of TRPA1 proteinPMID:21591660
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