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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2951
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcna3
Name: potassium voltage-gated channel subfamily A member 3
Acc ID: CHEBI:34027
Term: 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Definition: A diarylmethane that has formula C14H9Cl5.
Chemical ID: MESH:C016340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcna3decreases activityISOKCNA3 (Homo sapiens)6480464CTDo,p'-DDT results in decreased activity of KCNA3 proteinPMID:21362439
Kcna3multiple interactionsISOKCNA3 (Homo sapiens)6480464CTD[o,p'-DDT results in decreased activity of KCNA3 protein] which results in decreased import of ThalliumPMID:21362439
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