Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2626
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Fos
Name: Fos proto-oncogene, AP-1 transcription factor subunit
Acc ID: CHEBI:34027
Term: 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Definition: A diarylmethane that has formula C14H9Cl5.
Chemical ID: MESH:C016340
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Fosincreases expressionEXP 6480464CTDo,p'-DDT results in increased expression of FOS mRNAPMID:24096037
Fosaffects localizationISOFOS (Homo sapiens)6480464CTDo,p'-DDT affects the localization of FOS proteinPMID:34167450
Fosincreases expressionISOFos (Mus musculus)6480464CTDo,p'-DDT results in increased expression of FOS mRNAPMID:18840457 PMID:24096037
Fosmultiple interactionsISOFos (Mus musculus)6480464CTDo,p'-DDT results in increased expression of and results in increased activity of FOS proteinPMID:18840457
Go Back to source page   Continue to Ontology report