GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Esr2 | increases activity | EXP | | 6480464 | CTD | o,p'-DDT results in increased activity of ESR2 protein | PMID:9860891 | Esr2 | multiple interactions | EXP | | 6480464 | CTD | [o,p'-DDT co-treated with Dichlorodiphenyl Dichloroethylene co-treated with Methoxychlor co-treated with Endosulfan co-treated with DDT] results in increased activity of ESR2 protein | PMID:9860891 | Esr2 | decreases expression | ISO | Esr2 (Mus musculus) | 6480464 | CTD | o,p'-DDT results in decreased expression of ESR2 mRNA; o,p'-DDT results in decreased expression of ESR2 protein | PMID:28263910 | Esr2 | decreases expression | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | o,p'-DDT results in decreased expression of ESR2 mRNA | PMID:18700809 | Esr2 | increases activity | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | o,p'-DDT results in increased activity of ESR2 protein | PMID:15064155 PMID:26812056 | Esr2 | multiple interactions | ISO | ESR2 (Homo sapiens) | 6480464 | CTD | o,p'-DDT binds to and results in increased activity of ESR2 protein | PMID:16626760 PMID:9751507 | |
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