GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620161
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp26a1
Name: cytochrome P450, family 26, subfamily a, polypeptide 1
Acc ID: CHEBI:338412
Term: (-)-anisomycin
Definition: An antibiotic isolated from various Streptomyces species. It interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
CasRN: 22862-76-6
Chemical ID: MESH:D000841
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:7313766480464CTDAnisomycin inhibits the reaction [Tretinoin results in increased expression of CYP26A1 mRNA]

PMID:16038797
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