GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Agt | increases expression | EXP | | 6480464 | CTD | candesartan cilexetil results in increased expression of AGT protein modified form | PMID:22120037 | Agt | multiple interactions | EXP | | 6480464 | CTD | candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of AGT protein modified form]; candesartan cilexetil promotes the reaction [Methamphetamine results in increased expression of AGT protein] | PMID:27889505 PMID:33421459 | Agt | decreases activity | ISO | AGT (Homo sapiens) | 6480464 | CTD | candesartan cilexetil results in decreased activity of AGT protein | PMID:15361886 | Agt | multiple interactions | ISO | AGT (Homo sapiens) | 6480464 | CTD | candesartan cilexetil inhibits the reaction [AGT protein results in increased expression of ICAM1 mRNA]; candesartan cilexetil inhibits the reaction [AGT protein results in increased secretion of ICAM1 protein] | PMID:10517737 | | ||||||||||||||||||||||
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