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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2277 Species: Rattus norvegicus RGD Object: Gene Symbol: Casr Name: calcium-sensing receptor

Acc ID: CHEBI:33324 Term: strontium atom Definition: An alkaline earth metal atom that has formula Sr. CasRN: 7440-24-6 Chemical ID: MESH:D013324

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
increases response to substance	ISO	RGD:10291	6480464	CTD	CASR protein results in increased susceptibility to Strontium	PMID:15068510
affects activity	ISO	RGD:10291	6480464	CTD	Strontium affects the activity of CASR protein	PMID:15068510