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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735227
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gaa
Name: alpha glucosidase
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gaadecreases expressionEXP 6480464CTDbisphenol A results in decreased expression of GAA mRNAPMID:32145629 PMID:34947998
Gaaincreases expressionEXP 6480464CTDbisphenol A results in increased expression of GAA mRNAPMID:25181051
Gaaincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of GAA genePMID:28505145
Gaadecreases expressionISOGAA (Homo sapiens)6480464CTDbisphenol A results in decreased expression of GAA proteinPMID:37664457
Gaaincreases expressionISOGAA (Homo sapiens)6480464CTDbisphenol A results in increased expression of GAA proteinPMID:34186270 PMID:37567409
Gaamultiple interactionsISOGAA (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of GAA genePMID:31601247
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