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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727921
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Zbtb16
Name: zinc finger and BTB domain containing 16
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Zbtb16affects expressionEXP 6480464CTDbisphenol A affects the expression of ZBTB16 mRNAPMID:30903817 PMID:32145629
Zbtb16decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of ZBTB16 mRNAPMID:25181051 PMID:27178563 PMID:30816183 PMID:32528016
Zbtb16increases methylationEXP 6480464CTDbisphenol A results in increased methylation of ZBTB16 genePMID:28505145
Zbtb16affects expressionISOZBTB16 (Homo sapiens)6480464CTDbisphenol A affects the expression of ZBTB16 mRNAPMID:27010169
Zbtb16affects methylationISOZbtb16 (Mus musculus)6480464CTDbisphenol A affects the methylation of ZBTB16 promoterPMID:27334623
Zbtb16decreases expressionISOZBTB16 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of ZBTB16 mRNAPMID:27685785
Zbtb16increases expressionISOZbtb16 (Mus musculus)6480464CTDbisphenol A results in increased expression of ZBTB16 mRNAPMID:25594700 PMID:34585602
Zbtb16multiple interactionsISOZbtb16 (Mus musculus)6480464CTD[bisphenol A co-treated with Stigmasterol] results in decreased expression of ZBTB16 mRNA; bisphenol A inhibits the reaction [GW 4064 results in decreased expression of ZBTB16 mRNA]; NR1H4 gene mutant form inhibits the reaction [[bisphenol A co-treated with Stigmasterol] results in decreased expression of ZBTB16 mRNA]PMID:30245210
Zbtb16multiple interactionsISOZBTB16 (Homo sapiens)6480464CTD[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] affects the expression of ZBTB16 mRNAPMID:28628672
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