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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68996
Species: Homo sapiens
RGD Object: Gene
Symbol: CACNA1I
Name: calcium voltage-gated channel subunit alpha1 I
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
CACNA1Idecreases methylationEXP 6480464CTDbisphenol A results in decreased methylation of CACNA1I genePMID:31601247
CACNA1Iaffects expressionISOCacna1i (Mus musculus)6480464CTDbisphenol A affects the expression of CACNA1I mRNAPMID:25958630
CACNA1Iaffects expressionISOCacna1i (Rattus norvegicus)6480464CTDbisphenol A affects the expression of CACNA1I mRNAPMID:25181051
CACNA1Idecreases expressionISOCacna1i (Mus musculus)6480464CTDbisphenol A results in decreased expression of CACNA1I mRNAPMID:30951980 PMID:32156529
CACNA1Imultiple interactionsISOCacna1i (Mus musculus)6480464CTDESR2 protein affects the reaction [bisphenol A affects the expression of CACNA1I mRNA]PMID:25958630
CACNA1Imultiple interactionsISOCacna1i (Rattus norvegicus)6480464CTD[bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of CACNA1I mRNAPMID:25607892
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