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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628742
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lgi1
Name: leucine-rich, glioma inactivated 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lgi1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of LGI1 mRNAPMID:25181051
Lgi1increases expressionEXP 6480464CTDbisphenol A results in increased expression of LGI1 mRNAPMID:34947998
Lgi1increases methylationEXP 6480464CTDbisphenol A results in increased methylation of LGI1 genePMID:28505145
Lgi1increases expressionISOLgi1 (Mus musculus)6480464CTDbisphenol A results in increased expression of LGI1 mRNAPMID:25594700
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