GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Kcnq1 | decreases expression | EXP | | 6480464 | CTD | bisphenol A results in decreased expression of KCNQ1 mRNA | PMID:25181051 | Kcnq1 | increases methylation | EXP | | 6480464 | CTD | bisphenol A results in increased methylation of KCNQ1 gene | PMID:28505145 | Kcnq1 | multiple interactions | EXP | | 6480464 | CTD | [bisphenol A co-treated with Estradiol] results in increased expression of KCNQ1 mRNA | PMID:26496021 | Kcnq1 | decreases methylation | ISO | KCNQ1 (Homo sapiens) | 6480464 | CTD | bisphenol A results in decreased methylation of KCNQ1 gene | PMID:31601247 | Kcnq1 | decreases methylation | ISO | Kcnq1 (Mus musculus) | 6480464 | CTD | bisphenol A results in decreased methylation of KCNQ1 promoter | PMID:27312807 | Kcnq1 | increases expression | ISO | Kcnq1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased expression of KCNQ1 mRNA | PMID:31649729 | Kcnq1 | increases methylation | ISO | Kcnq1 (Mus musculus) | 6480464 | CTD | bisphenol A results in increased methylation of KCNQ1 promoter | PMID:27312807 | Kcnq1 | multiple interactions | ISO | KCNQ1 (Homo sapiens) | 6480464 | CTD | [bisphenol A co-treated with Fulvestrant] results in decreased methylation of KCNQ1 gene | PMID:31601247 | Kcnq1 | multiple interactions | ISO | Kcnq1 (Mus musculus) | 6480464 | CTD | [bisphenol A results in decreased methylation of KCNQ1 intron] which results in decreased abundance of 5-hydroxymethylcytosine | PMID:30044229 | |
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